Global Proteinase K Market

Proteinase K Market Insights

The global proteinase K market will register a remarkable growth in the 2020-2026 time frame at a CAGR percentage of 8.05. Proteinase K is a highly specific broad range serine protease manufactured from a fungus named Tritirachium album Limber. It is enzyme or reagent depends on the type of reaction which on application digests proteins and take off all the contaminants during the preparation of nucleic acid. Expeditious inactivation of nuclease activity by proteinase K end up protecting DNA and RNA from degradation during purification. Enzyme removal, PCR purification, bacterial genome purification, mitochondria isolation, and protein destruction in cell lysate (cell and tissue culture) are other applications of proteinase K in molecular biology. The activity of proteinase K towards denatured and native proteins is triggered by SDS, EDTA, and ureas. Tolerance from wide temperature and chemical range is most likely to cater to its application in agriculture, pharmaceutical, food, and biotechnology sectors.

Healthcare evolution and government expenditure in R & D techniques are giving a positive curve to the growth of the proteinase k market. Extended support from local and multinational players in the adoption and discovery of a new variety of products offering is creating significant demand for proteinase k on a positive note. Low cost of production, specificity, and excellent stability has uplifted the proteinase k popularity in the last few years.

The efficient detection of COVID-19 with the help of proteinase K pre-treatment activity has boosted the demand for the product in many severely affected regions. Brazil recently comes up with a discovery of COVID-19 testing without the involvement of the RNA extraction step as it requires skilled workers with sufficient funding. The new protocol involves proteinase K during sample pre-treatment thus discarding all the time and cost-consuming protocols.

Proteinase K Market: By Type of Therapeutic Area

The therapeutic area of proteinase K can be explained into infectious diseases, diabetes, oncology, cardiology, nephrology, autoimmune diseases, neurology, and other therapeutic areas. Infectious diseases accounted for the largest revenue of the proteinase K market. Wide clinical relevance and application of proteinase K in the detection of countless infectious diseases are building the demand for the product in this region. Research shows DNA incubation from HBV with proteinase K results in isolation of efficient DNA and much high yield in comparison to standard protocols. The growth of proteinase K is fastest in the neurology segment owing to high application in prion disease detection.

Proteinase K Market: By Form

Proteinase K market can be bifurcated into powder and liquid-based on the form of the product. The powder segment builds the highest proteinase K market in the year 2019 owing to notable advantages compared to the liquid segment. Powder segment has the physical isolation property of enzyme which help from autolytic degradation, oxidation, and denaturation of enzyme stimulated by the water-softening builders. However, enzyme resistance from chelating agents and detergents by the liquid segment is growing the segment demand at the fastest rate and expected to led the market in the conjecture time frame.

Proteinase K Market: By Region

Asia Pacific is anticipated to grow the proteinase K market at the fastest CAGR% between the 2020-2026 period. High target disorder prevalence along with a large customer percentage in the region is propelling the demand for the product. Currently, China and India are the most severely affected countries by COVID-19 which leads to a boost in the proteinase K demand for the analysis of the suspected individual sample.

North America shared the largest revenue in 2019 of the proteinase K market. Raising the prevalence of cancer patients end of bringing next-generation technology and PCR for disease detection at an early stage. This is expected to drive the demand for proteinase K and other enzymes and reagents required in NGS and PCR techniques.

Proteinase K Market Share and Competitor Analysis

The key players operating in the market include Merck KGaA, Codexis, F. Hoffmann-La Roche Ltd., Amano Enzymes, Advanced Enzymes Technologies Ltd., Biocatalysts Ltd., Amicogen, Dyadic International, BBI Solutions, Affymetrix, and American Laboratories among others.

Please note: This is not an exhaustive list of companies profiled in the report.

In October 2020, Merck KGaA launched Virus Express, a platform for the speedy development of cell and gene therapies. The platform provides a simplified upstream workflow with easy and adjustable processes.

In January 2020, Codexis, F collaborated with Alphazyme to bring set novel enzymes for the diagnostic and life science market. The company promised to bring 3 enzymes in which the first enzyme is focused to target NGS based diagnosis, manufacturing of RNA and RNA detected viral diagnostics.

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